Silvia Grottelli Selected Research

histidyl-proline diketopiperazine

1/2018	Potential Influence of Cyclo(His-Pro) on Proteostasis: Impact on Neurodegenerative Diseases.
8/2016	The Role of Cyclo(His-Pro) in Neurodegeneration.
6/2014	Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity.
3/2012	Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling.

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Silvia Grottelli Research Topics

Disease

4	Primary Hyperoxaluria (Oxaluria, Primary) 01/2022 - 01/2019
4	Neoplasms (Cancer) 01/2019 - 12/2012
3	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2020 - 08/2016
3	Prostatic Neoplasms (Prostate Cancer) 09/2017 - 12/2012
2	Primary hyperoxaluria type 1 01/2022 - 12/2019
2	Gyrate Atrophy 01/2021 - 11/2018
2	Inflammation (Inflammations) 06/2020 - 06/2014
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2018 - 08/2016
2	Neuroinflammatory Diseases 08/2016 - 06/2014
1	Kidney Calculi (Kidney Stone) 01/2022
1	Kidney Diseases (Kidney Disease) 01/2022
1	Rare Diseases (Rare Disease) 12/2019
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2019
1	Amyloidosis 01/2019
1	Proteostasis Deficiencies 01/2018
1	Muscular Atrophy (Muscle Atrophy) 02/2017
1	Atrophy 02/2017
1	Gliosis 06/2014
1	Otitis 03/2012
1	Pheochromocytoma 03/2012
1	Parkinson Disease (Parkinson's Disease) 11/2009

Drug/Important Bio-Agent (IBA)

4	histidyl-proline diketopiperazineIBA 01/2018 - 03/2012
3	Alanine-glyoxylate transaminase (alanine-glyoxylate aminotransferase)IBA 01/2022 - 12/2019
3	EnzymesIBA 01/2022 - 01/2019
3	Proteins (Proteins, Gene)FDA Link 04/2021 - 04/2014
2	glyoxylic acid (glyoxylate)IBA 01/2022 - 12/2019
2	Biological ProductsIBA 12/2019 - 08/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2014 - 12/2012
2	Succinic Acid (Succinate)IBA 04/2014 - 12/2012
2	Heme Oxygenase-1IBA 12/2012 - 03/2012
2	ParaquatIBA 03/2012 - 11/2009
1	OxalatesIBA 01/2022
1	LigandsIBA 01/2022
1	PyridoxalIBA 04/2021
1	Ornithine-Oxo-Acid Transaminase (Ornithine Aminotransferase)IBA 01/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2020
1	acetamidineIBA 06/2020
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2020
1	Cycloserine (Seromycin)FDA Link 12/2019
1	Calcium OxalateIBA 12/2019
1	Prealbumin (Transthyretin)IBA 01/2019
1	OrnithineIBA 11/2018
1	Transaminases (Aminotransferases)IBA 11/2018
1	InflammasomesIBA 01/2018
1	histidylprolineIBA 01/2018
1	Peroxynitrous Acid (Peroxynitrite)IBA 01/2018
1	AntibodiesIBA 09/2017
1	Endoplasmic Reticulum Chaperone BiPIBA 09/2017
1	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2017
1	UbiquitinIBA 02/2017
1	CalciumIBA 08/2016
1	DipeptidesIBA 06/2014
1	NeurotoxinsIBA 06/2014
1	quinone (benzoquinone)IBA 04/2014

Therapy/Procedure

1	Denervation 02/2017
1	Oral Administration 08/2016